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Next an 8-week oral NMN intervention at 300 mg/kg/day on male C57B1/6 mice, both carotid artery EDD and nitric oxide EDD have been restored to ordinary stage, like that of younger Manage mice. Again, the disorders of older mice just like the abundance of oxidative strain marker nitrotyrosine, lowered elastin and vascular SIRT1 exercise, all were re